国际权威肿瘤诊疗指南中病理诊断要求
1.早期或局部进展/非转移性NSCLC
2.转移性NSCLC
3.生物标志物
1
表皮生长因子受体(EGFR)突变
2
间变性淋巴瘤激酶(ALK)重排
3
ROS原癌基因1(ROS1)重排
4
BRAF突变
5
神经营养因子受体络氨酸激酶(NTRK)重排
上皮性肿瘤(epithelial tumours) |
乳头状瘤(papillomas) |
支气管乳头状瘤(bronchial papillomas) |
腺瘤(adenomas) |
硬化性肺细胞瘤(sclerosing pneumocytoma) |
肺泡性腺瘤(alveolar adenoma) |
细支气管腺瘤/纤毛黏液结节乳头状肿瘤(bronchial adenoma/ciliated muconodular papillary tumor) |
黏液性囊腺瘤(mucinous cystadenoma) |
黏液腺腺瘤(mucinous gland adenoma) |
前驱腺体病变(precursor glandular lesions) |
非典型腺瘤性增生(atypical adenomatous hyperplasia) |
原位腺癌(adenocarcinoma in situ) |
腺癌(adenocarcinomas) |
微浸润性腺癌(microinvasive adenocarcinoma) |
浸润性非黏液腺癌(invasive non-mucinous adenocarcinoma) |
浸润性黏液腺癌(invasive mucinous adenocarcinoma) |
胶样腺癌(colloid adenocarcinoma) |
胎儿型腺癌(fetal adenocarcinoma) |
肠型腺癌(entric-type adenocarcinoma) |
鳞状细胞前驱病变(squamous precursor lesions) |
鳞状细胞不典型增生和原位鳞癌(squamous dysplasia and carcinoma in situ) |
鳞状细胞癌(squamous cell carcinomas) |
鳞状细胞癌(squamous cell carcinoma) |
淋巴上皮样癌(lymphoepithelial carcinoma) |
大细胞癌(large cell carcinomas) |
大细胞癌(large cell carcinoma) |
腺鳞癌(adenosquamous carcinomas) |
腺鳞癌(adenosquamous carcinoma) |
肉瘤样癌(sarcomatoid carcinomas) |
多形性癌(pleomorphic carcinoma) |
肺母细胞瘤(pulmonary blastoma) |
癌肉瘤(carcinosarcoma) |
其他上皮肿瘤(other epithelial tumours) |
肺部NUT癌(NUT carcinoma of lung) |
胸部SMARCA4缺失的未分化肿瘤(thoracic SMARCA4-deficient undifferentiated tumor) |
涎腺型肿瘤(salivary gland-type tumors) |
多形性腺瘤(pleomorphic adenoma) |
腺样囊性癌(adenoid cystic carcinoma) |
上皮-肌上皮癌(epithelium-myoepithelial carcinoma) |
黏液表皮样癌(mucoepidermoid carcinoma) |
玻璃样变透明细胞癌(hyalinizing clear cell carcinoma) |
肌上皮瘤和肌上皮癌(myoepithelioma and myoepithelial carcinoma) |
肺神经内分泌肿瘤(lung neuroendocrine neoplasms) |
前驱病变(precursor lesion) |
弥漫性特发性肺神经内分泌细胞增生(diffuse idiopathic pulmonary neuroendocrine cell hyperplasia) |
神经内分泌肿瘤(neuroendocrine tumors) |
类癌/神经内分泌瘤(carcinoid/neuroendocrine tumor) |
神经内分泌癌(neuroendocrine carcinomas) 小细胞肺癌(small cell lung carcinoma) 大细胞神经内分泌癌(large cell neuroendocrine carcinoma) |
异位起源性肿瘤(tumours of ectopic tissues) |
黑色素瘤(melanoma) |
脑膜瘤(meningioma) |
肺间叶性肿瘤(mesenchymal tumours specific to the lung) |
肺错构瘤(pulmonary hamartoma) |
肺软骨瘤(pulmonary chondroma) |
弥漫性肺淋巴管瘤病(diffuse pulmonary lymphangiomatosis) |
胸膜肺母细胞瘤(pleuropneumonary blastoma) |
肺动脉内膜肉瘤(pulmonary artery intimal sarcoma) |
先天性支气管周肌纤维母细胞瘤(congenital peribronchial myofibroblastic tumour) |
EWSR1-CREB1融合的原发性肺黏液样肉瘤(primary pulmonary myxoid sarcoma with EWSR1-CREB1 fusion) |
血管周上皮细胞肿瘤(PEComatous tumours) 淋巴管平滑肌瘤病(lymphangioleiomyomatosis) PEComa(PEComa) |
淋巴造血系统肿瘤(haematolymphoid tumors) |
MALT淋巴瘤(MALT lymphoma) |
弥漫性大B细胞淋巴瘤(diffuse large B-cell lymphoma) |
淋巴瘤样肉芽肿病(lymphomatoid granulomatosis) |
血管内大B细胞淋巴瘤(intravascular large B-cell lymphoma) |
肺朗格汉斯细胞组织细胞增生症(pulmonary Langerhans cell histiocytosis) |
Erdheim-Chester病(Erdheim-Chester disease) |
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